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PCOS Test (EFP1)

£139.00

A simple finger-prick test for women who might have Polycystic Ovary Syndrome (PCOS), one of the main causes of female infertility.

 

A simple finger-prick test for women who might have Polycystic Ovary Syndrome (PCOS), one of the main causes of female infertility.

 

Which biomarkers are tested?

  • Follicle Stimulating Hormone (FSH)
  • Luteinizing Hormone (LH)
  • Estradiol (E2)
  • Anti Mullerian Hormone (AMH)
  • Glycated haemoglobin (HbA1C)
  • Testosterone
  • Dehydroepiandrosterone (DHEA-S)
  • Sex Hormone-Binding Globulin (SHBG)
  • Lipids

 

Who should take this test?

  • Women who have symptoms of Polycystic Ovary Syndrome (PCOS) like irregular periods, excess hair growth (usually in the face, chest, back or buttocks), thinning hair and hair loss from the head, oily skin or acne.

 

What is the process?

  1. Order online
  2. Receive a discrete test kit 
  3. Collect the sample
  4. Post the kit using free packaging provided
  5. Receive your results reviewed by our clinical team

 

Special instructions

Take your sample in the morning, between day 2 and 5 of your period.

If you don’t have periods, you can take the sample at any time of your cycle.

If you are taking hormone replacement or the contraceptive pill, the results may be affected. Consider taking the test during a break from these medications for more accurate results. 

If you use hormone gels or hormone pessaries, avoid collecting the sample from the finger usually used to manipulate these medications.

 

How long will it take to get the results?

Up to 2 working days

 

About PCOS Test

PCOS refers to Polycystic Ovarian Syndrome, a common condition affecting 1 in 10 women of reproductive age. In PCOS, the ovaries are bigger and have many follicles that contain immature eggs that never mature enough to trigger ovulation. It is the number one cause for non-ovulation and is often associated with infertility and metabolic disorders. Several hormones can be altered in this syndrome, and these are tested in this at-home finger-prick test.

Andreia Trigo RN

 

Follicle Stimulating Hormone (FSH) and Luteinizing Hormone (LH)

Luteinizing Hormone (LH) and Follicle Stimulating Hormone (FSH) are produced by the pituitary gland. FSH stimulates the ovaries to develop the follicles that contain the eggs, and LH is responsible for the final stages of egg maturation and its release from the ovaries (ovulation). In order for proper follicle and egg development to occur, FSH and LH each need to be present at certain levels and at specific times during the normal menstrual cycle.

Normally the LH to FSH ratio is about 1:1 – meaning the FSH and LH levels in the blood are similar. However, some women with PCOS present an LH level that is two or three times higher than their FSH level (this is called an elevated LH to FSH ratio of 2:1 or 3:1) which results in disruption of ovulation.

 

Estradiol (E2)

Estrogen is a female hormone that is secreted mainly by the ovaries and in small quantities by the adrenal glands.  The most active estrogen in the body is called estradiol (E2).  This hormone is responsible for the growth of reproductive organs and for egg development. As the follicles mature, more estrogen is produced. When a certain threshold of estrogen is reached, a feedback system triggers the hypothalamus and pituitary gland to release luteinizing hormone to trigger ovulation. Women with PCOS may have normal estradiol (E2) levels, which may be related to the high levels of insulin and testosterone (usually found in women with PCOS) that are sometimes converted to estrogen.

 

Anti Mullerian Hormone (AMH)

Anti Mullerian Hormone (AMH) is a glycoprotein hormone produced by the follicles in the ovaries. It correlates with the total number of antral follicles over both ovaries and is considered the earliest and most sensitive test of ovarian reserve. Women with PCOS often have elevated AMH levels, likely to be due to the high number of large follicles in the early stage of development.

 

Glycated haemoglobin (HbA1C)

Recent research shows that PCOS is probably caused by insulin resistance, which can be indicated by a high glucose level. Glycated haemoglobin test (HbA1c) measures the average blood glucose levels for the last two to three months. It can indicate whether you have or are at risk of developing diabetes. 

Testosterone

Testosterone is produced in small quantities by the ovaries. However, in women with PCOS, testosterone levels are usually moderately elevated, resulting in irregular periods, disrupted ovulation, excess hair growth (usually in the face, chest, back or buttocks), thinning hair and hair loss from the head.

Dehydroepiandrosterone (DHEA-S)

DHEA-S is the most abundant steroid hormone in the blood. It is secreted by the adrenal glands and it’s a precursor for several important hormones, including testosterone and oestradiol. Most women with PCOS tend to have high levels of DHEA-S.

Sex Hormone-Binding Globulin (SHBG)

Sex Hormone-Binding Globulin (SHBG) is a protein in the blood that binds to sex hormones like testosterone and estrogen, meaning that they are unavailable to be affect the cells. Measuring the level of SHBG in your blood gives important information about your levels of free or unbound hormones which are biologically active and available for use. The value of SHBG is normal to low in women with PCOS.

Lipids

Research suggests that women with PCOS are at a higher risk of developing abnormal lipid levels. Lipids are fats that are important constituents of cells and sources of energy. They are necessary for life, but abnormal levels may cause cardiovascular disease. This test measures the level of specific lipids in the blood: cholesterol and triglycerides which are used to assess your risk of developing cardiovascular disease.

 

 

 

The Small Book of Fertility Hormones

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