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Ovarian Rejuvenation: an innovative technique

Blood sample centrifuge
 
Blog post written in collaboration with our partners UR Vistahermosa
 
In this article, we spoke with Marta Varea from UR Vistahermosa to learn about this new technique: what is Ovarian Rejuvenation, what does this treatment entail, who can benefit from it, and more!

What is ovarian rejuvenation?

It is an innovative and experimental technique that aims to reverse primary ovarian ageing. The technique used is to obtain platelet-enriched plasma as a regenerative treatment that offers women the possibility of being mothers with their own eggs.


What does this treatment entail?

In the 1st consultation, we perform a Gynecological examination, an ultrasound with the follicular count, and an analysis for the determination of AMH. With the results of these first tests, each case is assessed and personalized. If the patient is suitable for the technique, we start the treatment, which is very simple, with the extraction of a blood sample that is processed in the laboratory by centrifugation, to obtain platelet-enriched plasma, rich in growth factors. This plasma is introduced into both ovaries through a transvaginal ovarian puncture, and in vitro fertilisation is performed in about two or three months.


What does this treatment entail?

In the 1st consultation, we perform a Gynecological examination, an ultrasound with the follicular count, and an analysis for the determination of AMH. With the results of these first tests, each case is assessed and personalized. If the patient is suitable for the technique, we start the treatment, which is very simple, with the extraction of a blood sample that is processed in the laboratory by centrifugation, to obtain platelet-enriched plasma, rich in growth factors. This plasma is introduced into both ovaries through a transvaginal ovarian puncture, and in vitro fertilisation is performed in about two or three months.


Who can benefit from the technique?

Patients with early menopause; women with low ovarian reserve; cases of premature ovarian failure


Are there any implications or side effects?

Considering that the treatment is performed with blood plasma, a component of the patient's own body, there are practically no side effects described in the literature, including no biological rejection.

However, although they have not been reported, the following risks associated with PRP exist:
  • Superficial or deep infection in the PRP application site;
  • Risks related to the blood draw (during the venipuncture, when processing the extracted blood, etc.);
  • Risks related to the PRP injection (injury to structures adjacent to the injection site), hematomas that will be reabsorbed in approximately 10 days with help from thrombocid cream.

Other risks and complications that may occur in exceptional cases:
  • Adverse reactions or intolerance to medication;
  • Peritoneal Infection;
  • Complications from the PRP injection: Severe haemorrhaging due to accidental puncture of blood vessels or the ovary itself. Puncture of an intestinal loop or other organs;
  • Ovarian torsion;
  • Pain, functional impotence or inability to work;
  • Failure to obtain oocytes after treatment.

Is one round of ovarian rejuvenation enough to see results?

We have seen so far that a single round of treatment is most of the times enough to see the results of the ovarian rejuvenation technique. Likewise, we will obtain better results if an assisted reproduction treatment is carried out afterwards.


What is the likelihood of success?

Nowadays it is still an experimental technique. In order to confirm the success rate we need to assess the case one by one, taking into account some other factors.


How long does the benefit last?

There is not a specific time, the response is assessed in 2-3 months.
 
 

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